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Christian's avatar

I assume you can’t absorb copper through the skin ? What about via old fashioned water copper pipes ? Negligible I guess ?

Robyn Chuter's avatar

Copper absorption through the skin is minimal, but it does occur - especially in women taking the oral contraceptive pill, interestingly enough: https://wilsondisease.org/can-copper-be-absorbed-through-the-skin/. The amount absorbed from copper bracelets is exceptionally small.

Copper water pipes were formerly a small but significant source of ingested copper. PVC pipes have replaced copper in many settings, but copper has greater durability, thermal properties, UV stability and resistance to bacteria than PVC, and of course it doesn't leach nasty volatile organic compounds into your drinking water. It's much more expensive, though. Good thing to invest in right now, if you've got some spare cash lying around!

Dr Rosemary Faire's avatar

Aha! Just discovered this part 5. After recommendations from our naturopath to up my husband's copper intake due to low serum copper and caeruloplasmin, I was taken aback by this research paper which found that high dietary copper coupled with high saturated fat was a bad idea for cognitive function: https://pmc.ncbi.nlm.nih.gov/articles/PMC9890213/ He has been prescribed lots of eggs, butter and cheese due to a very low cholesterol. What a web of influences!

Robyn Chuter's avatar

Is your husband taking zinc supplements? This could be a reason for his low serum copper and ceruloplasmin: see https://www.gastrojournal.org/article/0016-5085(88)90445-3/pdf.

Dr Rosemary Faire's avatar

Yes, we've both been on zinc picolinate (but not high doses) during the pandemonium, but I looked at records from 2012 when his haemolytic anaemia was first investigated, and even back then his caeruloplasmin, serum copper and 24hr urine copper were all low; but we weren't on zinc then and his RBC's are large not small. Maybe we should book a consult with you sometime? Complex story.

Robyn Chuter's avatar

Very complex indeed! I'd be more than happy to review your husband's case if he's open to it.

Robyn Chuter's avatar

I'll be blunt: any practitioner who believes that low serum cholesterol is a problem that should be treated is an idiot. And if their argument is that the brain requires cholesterol, it's quite frankly criminal negligence to be unaware that the brain manufactures its own cholesterol and maintains its own cholesterol pool which is kept separate from systemic cholesterol circulation by the blood-brain barrier.

Dr Rosemary Faire's avatar

Maybe it was the association of very low cholesterol with higher mortality which has been floating around... unpacked in this article: https://sigmanutrition.com/statement/low-cholesterol-increased-mortality-risk-clarifying-the-confusion/ He considers Malhotra a "quack" and statins are good? Hard for an ex-biologist to navigate all these controversies!

Robyn Chuter's avatar

Alan Flanagan's analysis of the relationship between low cholesterol and higher mortality is correct: it's reverse causation. I discussed this at length in https://robynchuter.substack.com/p/never-trust-always-verify-even-your and https://robynchuter.substack.com/p/is-low-cholesterol-bad-for-you?utm_source=publication-search.

I have misgivings about Malhotra. He's a show-pony who likes to jump to the front of the parade to give the impression that he's leading it.